Open Accessα(E)-Catenin Regulates BMP-7 Expression and Migration in Renal Epithelial Cells
Author(s) -
LaNita A. Nichols,
Anna Ślusarz,
Elizabeth A. GrunzBorgmann,
Alan Parrish
Publication year - 2014
Publication title -
american journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 85
eISSN - 1421-9670
pISSN - 0250-8095
DOI - 10.1159/000362250
Subject(s) - medicine , catenin , microbiology and biotechnology , cancer research , endocrinology , wnt signaling pathway , signal transduction , biology
The aging kidney has a decreased ability to repair following injury. We have shown a loss in expression of α-catenin in the aging rat kidney and hypothesize that decreased α-catenin expression in tubular epithelial cells results in diminished repair capacity.
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