Galectin-3 and PTEN Expression in Pancreatic Ductal Adenocarcinoma, Pancreatic Neuroendocrine Neoplasms and Gastrointestinal Tumors on Fine-Needle Aspiration Cytology | Zendy

Kun Jiang | Zendy; Diane Lawson | Zendy; C. M. S. Cohen | Zendy; Momin T. Siddiqui | Zendy

Open Access

Galectin-3 and PTEN Expression in Pancreatic Ductal Adenocarcinoma, Pancreatic Neuroendocrine Neoplasms and Gastrointestinal Tumors on Fine-Needle Aspiration Cytology

Author(s) -

Kun Jiang,

Diane Lawson,

C. M. S. Cohen,

Momin T. Siddiqui

Publication year - 2014

Publication title -

acta cytologica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.513

H-Index - 57

eISSN - 1938-2650

pISSN - 0001-5547

DOI - 10.1159/000362221

Subject(s) - pten , tensin , medicine , tissue microarray , pathology , neuroendocrine tumors , adenocarcinoma , gist , immunohistochemistry , galectin 3 , pancreas , stromal tumor , pancreatic cancer , cancer research , cancer , stromal cell , biology , pi3k/akt/mtor pathway , apoptosis , biochemistry

Galectin-3 has been implicated in the carcinogenesis of pancreatic ductal adenocarcinoma (PDAC). Its applicability in pancreatic fine-needle aspiration (FNA) in separating malignant from benign lesions has never been addressed. In addition, a correlation between Galectin-3 and tumor suppressor phosphatase and tensin homolog (PTEN) and their potential diagnostic value has never been tested.

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