Effect of the FTO rs9930506 Polymorphism on the Main Comorbidities of the Cardiorenal Metabolic Syndrome in an Elderly Spanish Cohort | Zendy

Eliécer Coto | Zendy; Beatriz Tavira | Zendy; Juan Gómez | Zendy; Salvador Tranche | Zendy; Carmen Díaz Corte | Zendy

Open Access

Effect of the <b><i>FTO</i></b> rs9930506 Polymorphism on the Main Comorbidities of the Cardiorenal Metabolic Syndrome in an Elderly Spanish Cohort

Author(s) -

Eliécer Coto,

Beatriz Tavira,

Juan Gómez,

Salvador Tranche,

Carmen Díaz Corte

Publication year - 2014

Publication title -

cardiorenal medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.661

H-Index - 21

eISSN - 1664-3828

pISSN - 1664-5502

DOI - 10.1159/000361054

Subject(s) - medicine , cohort , renal function , obesity , metabolic syndrome , type 2 diabetes , body mass index , single nucleotide polymorphism , overweight , odds ratio , diabetes mellitus , kidney disease , population , endocrinology , gastroenterology , genotype , biology , genetics , gene , environmental health

Fat mass and obesity-associated (FTO) gene polymorphisms have been linked to the risk of obesity and diabetes, two well-recognized risk factors for renal disease. Our aim was to determine whether a common FTO polymorphism was associated with a reduced estimated glomerular filtration rate (eGFR) independently of body mass index (BMI) and type 2 diabetes mellitus (T2DM) in a cohort of elderly individuals from the region of Asturias (Northern Spain; RENASTUR cohort).

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