Benefit of Cilostazol in Patients with High Risk of Bleeding: Subanalysis of Cilostazol Stroke Prevention Study 2
Author(s) -
Shinichiro Uchiyama,
Yukito Shinohara,
Yasuo Katayama,
Takenori Yamaguchi,
Shunnosuke Handa,
Kempei Matsuoka,
Yasuo Ohashi,
Norio Tanahashi,
Hiroko Yamamoto,
Chokoh Genka,
Yasuhisa Kitagawa,
Hideo Kusuoka,
K Nishimaru,
Motoo Tsushima,
Yukihiro Koretsune,
Tohru Sawada,
Chikuma Hamada
Publication year - 2014
Publication title -
cerebrovascular diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.221
H-Index - 104
eISSN - 1421-9786
pISSN - 1015-9770
DOI - 10.1159/000360811
Subject(s) - medicine , cilostazol , stroke (engine) , aspirin , hazard ratio , incidence (geometry) , confidence interval , proportional hazards model , cumulative incidence , lacunar stroke , cardiology , cohort , ischemic stroke , ischemia , mechanical engineering , physics , optics , engineering
The Cilostazol Stroke Prevention Study 2 (CSPS 2) showed that cilostazol significantly reduced the risk of stroke by 25.7% relative to aspirin, with significantly fewer hemorrhagic events, in patients with prior ischemic stroke, excluding cardioembolic stroke. However, whether the benefit of cilostazol is sustained in patients with a high risk of bleeding has not been examined.
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