Advanced Age Impairs Cardioprotective Function of Mesenchymal Stem Cell Transplantation from Patients to Myocardially Infarcted Rats
Author(s) -
Yu Liu,
Tao Liu,
Jinsong Han,
Zhonglu Yang,
Xiaodong Xue,
Hui Jiang,
Huishan Wang
Publication year - 2014
Publication title -
cardiology
Language(s) - English
Resource type - Journals
eISSN - 1421-9751
pISSN - 0008-6312
DOI - 10.1159/000360393
Subject(s) - mesenchymal stem cell , tunel assay , transplantation , medicine , myocardial infarction , immunohistochemistry , vascular endothelial growth factor , apoptosis , western blot , andrology , cardiology , pathology , vegf receptors , biology , biochemistry , gene
Mesenchymal stem cells (MSCs) have limited clinical therapeutic effects in older myocardial infarction (MI) patients. Thus, whether younger MSCs might confer greater protection is worth investigating.
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