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Preventing Catheter-Related Bacteremia with Taurolidine-Citrate Catheter Locks: A Systematic Review and Meta-Analysis
Author(s) -
Hongbo Liu,
Hongmei Liu,
Jing Deng,
Lihua Chen,
Yuan Lu,
Yong Wu
Publication year - 2014
Publication title -
blood purification
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 57
eISSN - 1421-9735
pISSN - 0253-5068
DOI - 10.1159/000360271
Subject(s) - medicine , bacteremia , catheter , meta analysis , adverse effect , bloodstream infection , heparin , intensive care medicine , randomized controlled trial , systematic review , surgery , medline , antibiotics , microbiology and biotechnology , biology , political science , law
Preliminary evidence from some studies suggests that taurolidine-citrate locks decrease catheter-related bacteremia (CRB), which is a major cause of morbidity and mortality in patients using intravascular catheters. No previous study has sought to summarize existing evidence on the use of taurolidine-citrate locks. A systematic review and meta-analysis were undertaken to determine whether taurolidine-citrate was more effective than heparin in the prevention of CRB.

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