Down-Regulation of miR-3928 Promoted Osteosarcoma Growth | Zendy

Haidong Xu | Zendy; Xiaozhou Liu | Zendy; Jianning Zhao | Zendy

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Down-Regulation of miR-3928 Promoted Osteosarcoma Growth

Author(s) -

Haidong Xu,

Xiaozhou Liu,

Jianning Zhao

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000358718

Subject(s) - cancer research , osteosarcoma , cell cycle , cyclin dependent kinase 6 , microrna , cell growth , erbb3 , biology , transfection , cancer , cell cycle checkpoint , medicine , cyclin d1 , gene , genetics , epidermal growth factor receptor

Osteosarcoma is the most common primary bone malignancy in children and young adults. Most failures of osteosarcoma treatment were due to resistance to chemotherapy. Development of new therapy required elucidation underlying molecular mechanism. Many miRNAs have been proved to be involved in the pathogenesis of osteosarcoma.

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