MicroRNA-127 Post-Transcriptionally Downregulates Sept7 and Suppresses Cell Growth in Hepatocellular Carcinoma Cells
Author(s) -
Jiansheng Zhou,
Shan Lu,
Shengsheng Yang,
Huan Chen,
Hanping Shi,
Mingyong Miao,
Binghua Jiao
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000358717
Subject(s) - microrna , gene knockdown , cell growth , carcinogenesis , cancer research , biology , cell cycle , hepatocellular carcinoma , apoptosis , cell , cancer , gene , genetics
Hepatocellular carcinoma is one of the most common cancers worldwide. It has been suggested that microRNAs, a class of small regulatory RNAs, are associated with tumorigenesis by targeting the mRNAs of hundreds of genes that modulate a variety of biological processes, including cellular differentiation, apoptosis, metabolism, and proliferation.
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