Analysis of <b><i>ADAM17</i></b> Polymorphisms and Susceptibility to Sporadic Abdominal Aortic Aneurysm
Author(s) -
You Li,
Cheng Yang,
Guoda Ma,
Lili Cui,
Xuefeng Gu,
Yanyan Chen,
Bin Zhao,
Haiyang Wang,
Keshen Li
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000358708
Subject(s) - genotype , abdominal aortic aneurysm , allele , medicine , pathophysiology , gastroenterology , biology , gene , genetics , aneurysm , surgery
Accumulating evidence suggests that the principal TNF-α converting enzyme, a disintegrin and metalloproteinase 17 (ADAM17), is involved in the development of human abdominal aortic aneurysm (AAA). However, the association between ADAM17 gene polymorphisms and AAA has not been explored. The present study was aimed to determine the association between ADAM17 promoter polymorphisms and AAA.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom