Open AccessMiR-142-3p Functions as a Potential Tumor Suppressor in Human Osteosarcoma by Targeting HMGA1
Author(s) -
Guoxing Xu,
Jin Wang,
Yixin Jia,
Feng Shen,
Han Wen-sheng,
Yifan Kang
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000358700
Subject(s) - osteosarcoma , cancer research , gene knockdown , downregulation and upregulation , microrna , suppressor , cell growth , cell culture , biology , cell , cancer , gene , genetics
Mounting evidence has shown that aberrant expression of miRNAs correlates with human cancers, and that miRNAs can function as tumor suppressors or oncogenes. Here, we investigated the role and mechanism of miR-142-3p in human osteosarcoma.
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