Fluctuations in Intraocular Pressure Increase the Trabecular Meshwork Extracellular Matrix | Zendy

Huan Zou | Zendy; Rongdi Yuan | Zendy; Qijun Zheng | Zendy; Yan Huo | Zendy; Min Lang | Zendy; Shu-Xing Ji | Zendy; Zheng Zheng | Zendy; Jian Ye | Zendy

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Fluctuations in Intraocular Pressure Increase the Trabecular Meshwork Extracellular Matrix

Author(s) -

Huan Zou,

Rongdi Yuan,

Qijun Zheng,

Yan Huo,

Min Lang,

Shu-Xing Ji,

Zheng Zheng,

Jian Ye

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000358691

Subject(s) - trabecular meshwork , intraocular pressure , extracellular matrix , fibronectin , h&e stain , glaucoma , laminin , ophthalmology , chemistry , elevated intraocular pressure , anatomy , endocrinology , immunohistochemistry , medicine , biochemistry

The trabecular meshwork (TM) tissue is constantly exposed to dynamic stress caused by intraocular pressure (IOP). The effects of such biomechanical stress on the TM have not been analyzed. This study developed an animal model of fluctuating IOP and evaluated the effects of these fluctuations on TM tissue.

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