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Tanshinone IIA Promotes Pulmonary Artery Smooth Muscle Cell Apoptosisin Vitroby Inhibiting the JAK2/STAT3 Signaling Pathway
Author(s) -
Minggang Chen,
Yumei Liu,
Dan Yi,
Liuping Wei,
Yumei Li,
Zhang Li
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000358682
Subject(s) - apoptosis , viability assay , hypoxia (environmental) , chemistry , signal transduction , stat3 , downregulation and upregulation , microbiology and biotechnology , vascular smooth muscle , flow cytometry , cancer research , pharmacology , medicine , biology , biochemistry , smooth muscle , organic chemistry , oxygen , gene
Tanshinone IIA inhibits the proliferation of pulmonary artery smooth muscle cells (PASMCs), but the potential mechanisms of its effects on PASMCs apoptosis remain unclear.

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