Inflammatory Microenvironment Changes the Secretory Profile of Mesenchymal Stem Cells to Recruit Mesenchymal Stem Cells
Author(s) -
Junchao Xing,
Tianyong Hou,
Huiyong Jin,
Fei Luo,
Zhengqi Change,
Zhiqiang Li,
Zhao Xie,
Jianzhong Xu
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000358663
Subject(s) - mesenchymal stem cell , microbiology and biotechnology , stem cell , biology , chemistry
Human bone-marrow mesenchymal stem cells (hBMSCs) are widely transplanted into inflammatory microenvironment to accelerate tissue regeneration. Transplanted hBMSCs recruit host hBMSCs through a poorly understood mechanism. This study was aimed to determine whether and how inflammatory microenvironment influenced the host-hBMSCs-recruiting capability of transplanted hBMSCs.
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