Hepatic Lipase Release is Inhibited by a Purinergic Induction of Autophagy
Author(s) -
Cynthia Chatterjee,
Daniel L. Sparks
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000358661
Subject(s) - autophagy , purinergic receptor , extracellular , microbiology and biotechnology , adenosine , purinergic signalling , secretion , chemistry , biology , biochemistry , receptor , adenosine receptor , apoptosis , agonist
We have shown that extracellular adenosine diphosphate (ADP) affects lipoprotein secretion from liver cells by stimulating cellular autophagic degradation. In this study, we investigated the effect of ADP and cellular autophagy on hepatic lipase (HL) release from human liver cells.
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