Expression of MicroRNA-29 and Collagen in Cardiac Muscle after Swimming Training in Myocardial-Infarcted Rats | Zendy

Stéphano Freitas Soares Melo | Zendy; Tiago Fernandes | Zendy; Valério Garrone Baraúna | Zendy; Katt C. Matos | Zendy; Alexandra A. S. Santos | Zendy; Paulo José Ferreira Tucci | Zendy; Edilamar Menezes de Oliveira | Zendy

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Expression of MicroRNA-29 and Collagen in Cardiac Muscle after Swimming Training in Myocardial-Infarcted Rats

Author(s) -

Stéphano Freitas Soares Melo,

Tiago Fernandes,

Valério Garrone Baraúna,

Katt C. Matos,

Alexandra A. S. Santos,

Paulo José Ferreira Tucci,

Edilamar Menezes de Oliveira

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000358642

Subject(s) - sed , ventricle , myocardial infarction , medicine , microrna , cardiac fibrosis , cardiac function curve , myocardial fibrosis , fibrosis , endocrinology , gene expression , cardiology , chemistry , heart failure , gene , biochemistry

Myocardial infarction (MI) is accompanied by cardiac growth, increased collagen deposition, cell death and new vascularization of the cardiac tissue, which results in reduced ventricular compliance. The MiRNA-29 family (29a, 29b, and 29c) targets mRNAs that encode collagens and other proteins involved in fibrosis. In this study we assessed the effects of swimming training (ST) on expression of the cardiac miRNA-29 family and on genes encoding collagen after MI in rats.

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