Secretoneurin Induces Airway Mucus Hypersecretion by Enhancing the Binding of EGF to NRP1 | Zendy

Rui Xu | Zendy; Qi Li | Zendy; Jia Zhou | Zendy; Xiangdong Zhou | Zendy; Juliy M. Perelman | Zendy; Victor P. Кolosov | Zendy

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Secretoneurin Induces Airway Mucus Hypersecretion by Enhancing the Binding of EGF to NRP1

Author(s) -

Rui Xu,

Qi Li,

Jia Zhou,

Xiangdong Zhou,

Juliy M. Perelman,

Victor P. Кolosov

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000358625

Subject(s) - mucin , neuropilin 1 , epidermal growth factor , receptor , mucus , epidermal growth factor receptor , phosphorylation , cell culture , chemistry , heparin binding egf like growth factor , secretion , stimulation , microbiology and biotechnology , biology , cancer research , endocrinology , biochemistry , vascular endothelial growth factor , ecology , genetics , vegf receptors

Secretoneurin(SN), a neuropeptide, has been considered a reliable marker of allergenic stimulation. However, the relationship between SN and the secretion of airway mucin remains unclear. In this study, we aimed to examine the in vitro relationship between SN and airway mucin over synthesis, as well as the signaling pathways involved.

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