Management of Bone Metastases in Patients with Castration-Resistant Prostate Cancer | Zendy

Richard Cathomas | Zendy; Zoltán Bajory | Zendy; Mounira Bouzid | Zendy; Ahmed El Ghoneimy | Zendy; Silke Gillessen | Zendy; Frederico Gonçalves | Zendy; Gabriel Kacsó | Zendy; Gero Kramer | Zendy; Piotr Milecki | Zendy; Dalibor Pacík | Zendy; Wahid Tantawy | Zendy; Krzystof Lesniewski-Kmak | Zendy

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Management of Bone Metastases in Patients with Castration-Resistant Prostate Cancer

Author(s) -

Richard Cathomas,

Zoltán Bajory,

Mounira Bouzid,

Ahmed El Ghoneimy,

Silke Gillessen,

Frederico Gonçalves,

Gabriel Kacsó,

Gero Kramer,

Piotr Milecki,

Dalibor Pacík,

Wahid Tantawy,

Krzystof Lesniewski-Kmak

Publication year - 2014

Publication title -

urologia internationalis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.771

H-Index - 53

eISSN - 1423-0399

pISSN - 0042-1138

DOI - 10.1159/000358258

Subject(s) - medicine , prostate cancer , spinal cord compression , radiation therapy , management of prostate cancer , cancer , oncology , surgery , spinal cord , psychiatry

Bone metastases are a very common problem in prostate cancer. They are associated with considerable morbidity, adversely affect quality of life and frequently lead to advanced bone events (so-called skeletal-related events, SREs); SREs include fractures, spinal cord compression and the requirement for bone surgery or bone radiation. The aim of this paper was to evaluate currently available treatment options in the prevention and management of SREs and bone metastases in men with castration-resistant prostate cancer and to outline the importance of interdisciplinary management strategies. It also discusses the diagnostic workup of osseous metastases and practical considerations for the utilization of bone-targeted therapies in accordance with current guidelines to provide a consensus for special and/or difficult clinical situations.

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