Interleukin 28B Gene Polymorphisms and Epstein-Barr Virus-Associated Lymphoproliferative Diseases | Zendy

Ela M. Akay | Zendy; Mauli Patel | Zendy; Tim Conibear | Zendy; Turren Chaggar | Zendy; Tanzina Haque | Zendy

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Interleukin 28B Gene Polymorphisms and Epstein-Barr Virus-Associated Lymphoproliferative Diseases

Author(s) -

Ela M. Akay,

Mauli Patel,

Tim Conibear,

Turren Chaggar,

Tanzina Haque

Publication year - 2014

Publication title -

intervirology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.641

H-Index - 61

eISSN - 1423-0100

pISSN - 0300-5526

DOI - 10.1159/000357326

Subject(s) - genotype , mononucleosis , single nucleotide polymorphism , epstein–barr virus , immunology , hepatitis b virus , biology , hepatitis c virus , virus , virology , medicine , gene , genetics

Single-nucleotide polymorphisms (SNPs) near the interleukin (IL) 28B gene encoding a type III interferon (IFN-λ) are the most important genetic predictors of treatment response to hepatitis C virus (HCV). This retrospective study was undertaken to determine any association between IL28B SNPs and the development of viraemia in Epstein-Barr virus (EBV)-driven acute infectious mononucleosis (IM) and post-transplant lymphoproliferative disease (PTLD).

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