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Transthoracic ultrasound (US) is an important instrument to identify pleural effusions and safely conduct invasive procedures. It also allows systematic scanning of the pleural surface, though its value remains uncertain for differentiation between malignant (MPE) and nonmalignant pleural effusion (non-MPE) in routine clinical practice.

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The Diagnostic Value of Transthoracic Ultrasonographic Features in Predicting Malignancy in Undiagnosed Pleural Effusions: A Prospective Observational Study