Open AccessAkt2- and ETS1-Dependent IP3 Receptor 2 Expression in Dendritic Cell Migration
Author(s) -
Wenting Yang,
Meerim K. Nurbaeva,
Evi Schmid,
Antonella Russo,
Ahmad Almilaji,
Kalina Szteyn,
Jing Yan,
Caterina Faggio,
Ekaterina Shumilina,
Florian Läng
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000356664
Subject(s) - akt2 , chemistry , microbiology and biotechnology , protein kinase b , signal transduction , akt1 , biology
The protein kinase Akt2/PKBβ is a known regulator of macrophage and dendritic cell (DC) migration. The mechanisms linking Akt2 activity to migration remained, however, elusive. DC migration is governed by Ca(2+) signaling. We thus explored whether Akt2 regulates DC Ca(2+) signaling.
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