Overexpression of miR-126 Inhibits the Activation and Migration of HSCs through Targeting CRK | Zendy

Xu-Hua Gong | Zendy; Chao Chen | Zendy; Peng Hou | Zendy; Songcheng Zhu | Zendy; Chaoqun Wu | Zendy; Chenlin Song | Zendy; Ni Wu | Zendy; Jiangfeng Hu | Zendy; Dingkang Yao | Zendy; Jiuhong Kang | Zendy; Liang Zhu | Zendy

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Overexpression of miR-126 Inhibits the Activation and Migration of HSCs through Targeting CRK

Author(s) -

Xu-Hua Gong,

Chao Chen,

Peng Hou,

Songcheng Zhu,

Chaoqun Wu,

Chenlin Song,

Ni Wu,

Jiangfeng Hu,

Dingkang Yao,

Jiuhong Kang,

Liang Zhu

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000356653

Subject(s) - adapter molecule crk , microrna , blot , immunostaining , transfection , cell growth , microbiology and biotechnology , biology , cell migration , cell , signal transduction , chemistry , cell culture , immunohistochemistry , immunology , gene , signal transducing adaptor protein , biochemistry , genetics

MicroRNAs (miRNAs) have been shown to play essential roles in HSCs activation which contributes to hepatic fibrosis. Our previous miRNA microarray results suggested that miR-126 might be decreased during HSCs activation as other studies. The aim of this study is to investigate the role of miR-126 during HSCs activation.

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