The Gene Polymorphism of LOX1 Predicts the Incidence of LVH in Patients with Essential Hypertension
Author(s) -
Xiaolin Xu,
Xuwei Hou,
Yixiu Liang,
Li Fan,
Liewen Pang,
Guoqian Huang,
Jiechun Huang,
Meng Shi,
Xiaotian Sun,
Yiqing Wang
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000356652
Subject(s) - left ventricular hypertrophy , single nucleotide polymorphism , medicine , genotype , snp , polymorphism (computer science) , cardiology , essential hypertension , gene polymorphism , endocrinology , biology , gene , blood pressure , genetics
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) has been shown to play an important role in cardiac remodeling under different pathologic conditions. The role of genetic polymorphisms in the LOX1 gene, however, remains unclear in the development of left ventricular hypertrophy (LVH) for patients with hypertension.
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