Transplantation of <b><i>N</i></b>-Acetyl Aspartyl-Glutamate Synthetase-Activated Neural Stem Cells after Experimental Traumatic Brain Injury Significantly Improves Neurological Recovery
Author(s) -
Mingfeng Li,
Xinlong Liu,
Haiyan Yue,
Weiming Xiong,
Jianfeng Gu,
Mao Xu
Publication year - 2013
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000356611
Subject(s) - neural stem cell , tunel assay , transplantation , traumatic brain injury , glutamate receptor , apoptosis , tumor necrosis factor alpha , biology , medicine , stem cell , endocrinology , biochemistry , microbiology and biotechnology , receptor , psychiatry
Neural stem cells (NSCs) hold considerable potential as a therapeutic tool for repair of the damaged nervous system. In the current study, we examined whether transplanted N-acetyl aspartyl-glutamate synthetase (NAAGS)-activated NSCs (NAAGS/NSCs) further improve neurological recovery following traumatic brain injury (TBI) in Sprague-Dawley rats.
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