Phospholipid Scramblase 1 Functionally Interacts with Angiogenin and Regulates Angiogenin-Enhanced rRNA Transcription | Zendy

Junqiao Zhu | Zendy; Jinghao Sheng | Zendy; Haojie Dong | Zendy; Lan Kang | Zendy; Jian Ang | Zendy; Zhengping Xu | Zendy

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Phospholipid Scramblase 1 Functionally Interacts with Angiogenin and Regulates Angiogenin-Enhanced rRNA Transcription

Author(s) -

Junqiao Zhu,

Jinghao Sheng,

Haojie Dong,

Lan Kang,

Jian Ang,

Zhengping Xu

Publication year - 2013

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000356604

Subject(s) - phospholipid scramblase , angiogenin , microbiology and biotechnology , transcription (linguistics) , biology , nucleolus , transcription factor , cytoplasm , gene , angiogenesis , genetics , phosphatidylserine , phospholipid , linguistics , philosophy , membrane

Angiogenin (ANG) can translocate to the target cell nucleus and accumulate in the nucleolus to enhance rRNA transcription, thus promoting cell proliferation. However, the regulation of ANG-enhanced rRNA transcription remains unknown. Previously we identified phospholipid scramblase 1 (PLSCR1) as a potential ANG-interacting protein in yeast two-hybrid screening.

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