Open AccessHIF1α Genetic Variants and Protein Expressions Determine the Response to Platinum Based Chemotherapy and Clinical Outcome in Patients with Advanced NSCLC
Author(s) -
Fenglei Wu,
Jian Zhang,
Yi Liu,
Yigong Zheng,
Nan Hu
Publication year - 2013
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000356593
Subject(s) - chemotherapy , immunohistochemistry , oncology , lung cancer , medicine , genotype , non small cell lung cancer (nsclc) , gene , biology , a549 cell , genetics
To investigate whether the hypoxia-inducible factor-1α (HIF-1α) genetic variants and protein expression affect the chemotherapy response and the clinical outcome of patients with advanced non-small cell lung cancer (NSCLC).
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