Cell Volume Regulation and Apoptotic Volume Decrease in Rat Distal Colon Superficial Enterocytes
Author(s) -
Stefania Antico,
Maria Giulia Lionetto,
Maria Elena Giordano,
Roberto Caricato,
T. Schettino
Publication year - 2013
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000356592
Subject(s) - apoptosis , propidium iodide , microbiology and biotechnology , chemistry , iberiotoxin , annexin , biology , programmed cell death , biophysics , biochemistry , potassium channel
The colon epithelium is physiologically exposed to osmotic stress, and the activation of cell volume regulation mechanisms is essential in colonocyte physiology. Moreover, colon is characterized by a high apoptotic rate of mature cells balancing the high division rate of stem cells.
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