Open AccessCell-Free DNA Analysis for Trisomy Risk Assessment in First-Trimester Twin Pregnancies
Author(s) -
M. M. Gil,
M.S. Quezada,
B. Bregant,
Argyro Syngelaki,
K. H. Nicolaides
Publication year - 2013
Publication title -
fetal diagnosis and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.976
H-Index - 60
eISSN - 1421-9964
pISSN - 1015-3837
DOI - 10.1159/000356495
Subject(s) - medicine , trisomy , cell free fetal dna , fetus , prospective cohort study , obstetrics , aneuploidy , gestation , pregnancy , gynecology , prenatal diagnosis , andrology , chromosome , biology , genetics , gene
To examine the clinical implementation of chromosome-selective sequencing of cell-free DNA (cfDNA) in maternal blood and an algorithm that relies on the lower fetal fraction contribution of the 2 fetuses in the assessment of risk for trisomies in twin pregnancies.
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