Proteomic Analysis of Human-Derived Cell Culture Supplements | Zendy

Jasmin Kemptner | Zendy; Karin Witzeneder | Zendy; Simone Hennerbichler | Zendy; Christian Gabriel | Zendy

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Proteomic Analysis of Human-Derived Cell Culture Supplements

Author(s) -

Jasmin Kemptner,

Karin Witzeneder,

Simone Hennerbichler,

Christian Gabriel

Publication year - 2013

Publication title -

transfusion medicine and hemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 39

eISSN - 1660-3818

pISSN - 1660-3796

DOI - 10.1159/000356241

Subject(s) - chemistry , cell culture , fetal bovine serum , microbiology and biotechnology , cell growth , gel electrophoresis , in vitro , medicine , endocrinology , biology , biochemistry , genetics

Development of cell therapy and advanced therapy medicinal products depends on in vitro expansion of human cells in fetal bovine serum (FBS) supplemented media. Human-derived supplements, such as human serum (huS) and human platelet lysate (hPL), represent suitable alternatives to FBS. Various studies demonstrated that the use of these human alternatives result in comparable or even improved proliferation and expansion ratios.

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