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Impaired Leukocytes Autophagy in Chronic Kidney Disease Patients
Author(s) -
WeiTing Chen,
KuoChun Hung,
MingShien Wen,
Po-Yaur Hsu,
TienHsing Chen,
HorngDar Wang,
JiTseng Fang,
ShianSen Shie,
ChaoYung Wang
Publication year - 2013
Publication title -
cardiorenal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.661
H-Index - 21
eISSN - 1664-3828
pISSN - 1664-5502
DOI - 10.1159/000356212
Subject(s) - medicine , autophagy , atg5 , endocrinology , kidney disease , kidney , biology , apoptosis , biochemistry
Proteins and cytoplasmic organelles undergo degradation and recycling via autophagy; its role in patients with chronic kidney disease (CKD) is still unclear. We hypothesize that impaired kidney function causes autophagy activation failure.

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