An Integrated Stroke Model with a Consistent Penumbra for the Assessment of Neuroprotective Interventions | Zendy

Dong Yang | Zendy; Yukako Nakajo | Zendy; Koji Iihara | Zendy; Hiroharu Kataoka | Zendy; Jyoji Nakagawara | Zendy; Qiang Zhao | Zendy; Hiroji Yanamoto | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

An Integrated Stroke Model with a Consistent Penumbra for the Assessment of Neuroprotective Interventions

Author(s) -

Dong Yang,

Yukako Nakajo,

Koji Iihara,

Hiroharu Kataoka,

Jyoji Nakagawara,

Qiang Zhao,

Hiroji Yanamoto

Publication year - 2013

Publication title -

european neurology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.573

H-Index - 77

eISSN - 1421-9913

pISSN - 0014-3022

DOI - 10.1159/000356048

Subject(s) - penumbra , medicine , ischemia , lesion , neuroprotection , occlusion , stroke (engine) , anesthesia , cardiology , surgery , mechanical engineering , engineering

A longer period of vessel occlusion reduces the coefficient of variation of the infarct lesion size ['infarct variation coefficient' (IVC)] due to a gradual expansion of the lesion within a limited territory defined by the vascular anatomy, but it increases the mortality rate. A crucial issue in the induction of experimental focal cerebral ischemia has been to achieve a low IVC value and a low mortality rate. We attempted to improve IVC and mortality using the 3-vessel occlusion model.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research