Open AccessDownregulation of MicroRNA-19b Contributes to Angiotensin II-Induced Overexpression of Connective Tissue Growth Factor in Cardiomyocytes
Author(s) -
Song Gao,
Tiewen Liu,
Zhe Wang,
Zhenyu Jiao,
Jun Cai,
Hongjie Chi,
Xinchun Yang
Publication year - 2013
Publication title -
cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.547
H-Index - 63
eISSN - 1421-9751
pISSN - 0008-6312
DOI - 10.1159/000355429
Subject(s) - ctgf , downregulation and upregulation , telmisartan , angiotensin ii , endocrinology , western blot , connective tissue , medicine , microrna , chemistry , growth factor , receptor , biology , gene , biochemistry , genetics , blood pressure
The present study was designed to decipher the molecular mechanisms underlying angiotensin (Ang) II-induced overexpression of connective tissue growth factor (CTGF) in cultured cardiomyocytes.
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