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Systemic lupus erythematosus (SLE) is an autoimmune multisystem disease characterized by the development of antinuclear antibodies. Nowadays considered outdated, lupus erythematosus (LE) cell preparation served as a screening test for SLE for decades. However, the importance of discovering LE cells on routine cytology cannot be overemphasized.

Lupus Erythematosus Cells in Bone Marrow: The Only Clue to a Previously Unsuspected Diagnosis of Systemic Lupus Erythematosus