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Clinical Features and Prognostic Factors in Severe Cutaneous Drug Reactions
Author(s) -
MinSuk Yang,
Min-Gyu Kang,
JaeWoo Jung,
WooJung Song,
Hye–Ryun Kang,
SangHeon Cho,
KyungUp Min
Publication year - 2013
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000354918
Subject(s) - toxic epidermal necrolysis , medicine , leukocytosis , scars , odds ratio , dermatology , carbamazepine , confidence interval , population , gastroenterology , surgery , epilepsy , environmental health , psychiatry
Severe cutaneous adverse reactions (SCARs) include Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS). SJS and TEN (SJS/TEN) and DRESS are thought to be different diseases; however, they share some clinical and laboratory features. Although SCORTEN serves as an excellent prognostic marker for SJS/TEN, there is still a need for development of other prognostic markers for SCARs.

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