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The Role of Aquaporin 1 Activated by cGMP in Myocardial Edema Caused by Cardiopulmonary Bypass in Sheep
Author(s) -
Fangbao Ding,
Yumei Yan,
Chunrong Bao,
Jianbing Huang,
Ju Mei,
Hao Liu,
Nan Ma,
Junwen Zhang
Publication year - 2013
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000354530
Subject(s) - cardiopulmonary bypass , cardiology , medicine , pulmonary edema , edema , anesthesia , lung
Most cardiac procedures involve the use of cardiopulmonary bypass (CPB), which pumps oxygenated blood to the body while the heart and lungs are isolated. CPB can cause profound alterations V in the homeostasis of physiological fluids, which often results in myocardial edema. In our study, we used sheep CPB model of in vivo and in vitro to assess the relationship between cGMP and AQP1 during CPB.

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