The Function Role of miR-181a in Chemosensitivity to Adriamycin by Targeting Bcl-2 in Low-Invasive Breast Cancer Cells | Zendy

Ying Zhu | Zendy; Jian Wu | Zendy; Shuchun Li | Zendy; Rong Ma | Zendy; Haixia Cao | Zendy; Minghua Ji | Zendy; Changwen Jing | Zendy; Jinhai Tang | Zendy

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The Function Role of miR-181a in Chemosensitivity to Adriamycin by Targeting Bcl-2 in Low-Invasive Breast Cancer Cells

Author(s) -

Ying Zhu,

Jian Wu,

Shuchun Li,

Rong Ma,

Haixia Cao,

Minghua Ji,

Changwen Jing,

Jinhai Tang

Publication year - 2013

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000354521

Subject(s) - cancer research , transfection , apoptosis , carcinogenesis , biology , breast cancer , annexin , gene silencing , doxorubicin , cancer , untranslated region , cell culture , chemotherapy , gene , messenger rna , genetics

miR-181a is involved in immunity, metabolism, tumor suppression or carcinogenesis reported by many other studies. However, its role in the development of chemosensitivity to adriamycin in low-invasive breast cancer cells remains unclear. The aim of this study is to define the function role of miR-181a in promoting the efficacy of adriamycin-based neoadjuvant chemotherapy.

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