Downregulation of Clusterin Expression in Human Testicular Seminoma | Zendy

Bianjiang Liu | Zendy; Min Han | Zendy; Jiexiu Zhang | Zendy; Pei Lu | Zendy; Jie Li | Zendy; Ninghong Song | Zendy; Zengjun Wang | Zendy; Changjun Yin | Zendy; Wei Zhang | Zendy

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Downregulation of Clusterin Expression in Human Testicular Seminoma

Author(s) -

Bianjiang Liu,

Min Han,

Jiexiu Zhang,

Pei Lu,

Jie Li,

Ninghong Song,

Zengjun Wang,

Changjun Yin,

Wei Zhang

Publication year - 2013

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000354511

Subject(s) - clusterin , seminoma , western blot , immunohistochemistry , biology , testicular cancer , real time polymerase chain reaction , pathology , downregulation and upregulation , cancer , andrology , cancer research , medicine , apoptosis , gene , biochemistry , chemotherapy

Clusterin, a heterodimeric glycoprotein of approximately 80 kDa, exists extensively in human body fluids. The abnormal expression of clusterin is closely related to the occurrence, progression, and prognosis of tumors. Up to now, few studies have focused on clusterin in human testicular cancer. This study describes an extensive exploration of the presence and expression of clusterin in testicular seminoma.

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