Open AccessUpregulation of TRPC1 Contributes to Contractile Function in Isoproterenol-induced Hypertrophic Myocardium of Rat
Author(s) -
Mo-Si Chen,
JunHua Xiao,
Yong Wang,
Bo-Ming Xu,
Lu Gao,
Jialing Wang
Publication year - 2013
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000354498
Subject(s) - medicine , trpc1 , ventricle , endocrinology , cardiac function curve , muscle hypertrophy , chemistry , ion channel , heart failure , receptor
The transient receptor potential canonical channel 1 (TRPC1) is a crucial component of the stretch-activated ion channels (SACs). The objective of this research was to demonstrate the contribution of TRPC1 in maintaining cardiac contractile function in the hypertrophic myocardium.
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