Kruppel-Like Factor 2 Regulates Dendritic Cell Activation in Patients with Acute Coronary Syndrome
Author(s) -
Hongcheng Fang,
Jing Lin,
Lei Wang,
Peiyi Xie,
Xiaoyan Wang,
FU Jian-yun,
Wen Ai,
Shaoyuan Chen,
Fei Chen,
Fengxiao Zhang,
Yousu Su,
Dazhu Li
Publication year - 2013
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000354496
Subject(s) - klf2 , cd80 , proinflammatory cytokine , acute coronary syndrome , medicine , transcription factor , immunology , dendritic cell , cd40 , microbiology and biotechnology , cancer research , inflammation , biology , immune system , in vitro , myocardial infarction , biochemistry , cytotoxic t cell , gene
Dendritic cells (DCs) activation is important in atherosclerosis and coronary heart disease, but the mechanisms regulating activation of dendritic cells remain largely unclear. The aim of this study was to evaluate the effect of transcription factor Kruppel-like factor 2 (KLF2) in the proinflammatory activation of DCs in acute coronary syndrome.
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