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Neural Ganglioside GD2+Cells Define a Subpopulation of Mesenchymal Stem Cells in Adult Murine Bone Marrow
Author(s) -
Jie Xu,
Wenjun Fan,
Xi Xiang Tu,
Teng Zhang,
Zhi Hou,
Tao Guo,
Xin Shu,
Xi Luo,
Yang Liu,
Fei Peng,
Chang Wang,
Lingzhi Xu,
Han Zhou,
Quentin Liu
Publication year - 2013
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000354492
Subject(s) - mesenchymal stem cell , bone marrow , clonogenic assay , flow cytometry , biology , population , stem cell , microbiology and biotechnology , ganglioside , homeobox protein nanog , chemistry , immunology , cell , medicine , biochemistry , embryonic stem cell , induced pluripotent stem cell , environmental health , gene
Due to the lack of specific markers, the isolation of pure mesenchymal stem cells (MSCs) from murine bone marrow remains an unsolved problem. The present study explored whether the neural ganglioside GD2 could serve as a single surface marker to uniquely distinguish murine bone marrow MSCs (mBM-MSCs) from other marrow elements.

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