Open AccessFree Fatty Acids Inhibit Protein Tyrosine Phosphatase 1B and Activate Akt
Author(s) -
Eisuke Shibata,
Takeshi Kanno,
Ayako Tsuchiya,
Kohzo Kuribayashi,
Chiharu Tabata,
Takashi Nakano,
Tomoyuki Nishizaki
Publication year - 2013
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000354489
Subject(s) - protein kinase b , phosphorylation , phosphatase , pi3k/akt/mtor pathway , biochemistry , protein phosphatase 2 , wortmannin , protein tyrosine phosphatase , chemistry , biology , signal transduction
Accumulating evidence has suggested that free fatty acids (FFAs) interact with protein kinases and protein phosphatases. The present study examined the effect of FFAs on protein phosphatases and Akt.
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