Acetylcholine Mediates AMPK-Dependent Autophagic Cytoprotection in H9c2 Cells During Hypoxia/Reoxygenation Injury | Zendy

Mei Zhao | Zendy; Lei Sun | Zendy; XiaoJiang Yu | Zendy; Miao Yi | Zendy; Jinjun Liu | Zendy; Hao Wang | Zendy; Jun Ren | Zendy; Weijin Zang | Zendy

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Acetylcholine Mediates AMPK-Dependent Autophagic Cytoprotection in H9c2 Cells During Hypoxia/Reoxygenation Injury

Author(s) -

Mei Zhao,

Lei Sun,

XiaoJiang Yu,

Miao Yi,

Jinjun Liu,

Hao Wang,

Jun Ren,

Weijin Zang

Publication year - 2013

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000354464

Subject(s) - autophagy , ampk , cytoprotection , pi3k/akt/mtor pathway , chemistry , viability assay , microbiology and biotechnology , apoptosis , pharmacology , phosphorylation , biology , protein kinase a , biochemistry

Acetylcholine (ACh), a neurotransmitter of vagal nerve, offers tolerance to ischemia/reperfusion injury. Given the regulation of autophagy in cardioprotection, this study was to examine the role of autophagy in ACh-elicited protection against hypoxia/reoxygenation (HR) injury.

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