Open AccessNm23-H1 Regulates Glucose-Stimulated Insulin Secretion in Pancreatic β-Cells via Arf6-Rac1 Signaling Axis
Author(s) -
Rajakrishnan Veluthakal,
David M. Kaetzel,
Anjaneyulu Kowluru
Publication year - 2013
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000354457
Subject(s) - gene knockdown , rac1 , microbiology and biotechnology , pak1 , biology , insulin , small interfering rna , kinase , small gtpase , secretion , signal transduction , endocrinology , biochemistry , transfection , gene
A growing body of evidence implicates novel roles for nm23-like proteins in the regulation of cellular functions. However, roles of these proteins in islet function and glucose-stimulated insulin secretion (GSIS) remain largely unknown.
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