miRNAs: Biogenesis, Origin and Evolution, Functions on Virus-Host Interaction
Author(s) -
Zhuo Yang,
Guohui Gao,
Jian an Shi,
Xuexue Zhou,
Xiaofeng Wang
Publication year - 2013
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000354455
Subject(s) - biology , microrna , biogenesis , virus , function (biology) , host (biology) , context (archaeology) , computational biology , genetics , gene , paleontology
MicroRNAs (miRNAs) are small endogenous non-coding functional RNAs. They can play vital roles in post-transcriptional regulating mRNAs transcripts in nearly all biological processes. More and more reports on miRNAs come from different species (animal, plant, bacteria, virus) in the researches in development, immunity, apoptosis, tumor, virus-host interaction. These recent findings provide new insights into the roles of miRNAs as well as their function. This review outlines the ever-deepening understanding of miRNAs (biogenesis, origin, evolution), and discusses functions from host and viral miRNAs in the context of virus-host interaction.
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