Patho-Epigenetics | Zendy

János Minárovits | Zendy; Hans Helmut Niller | Zendy

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Patho-Epigenetics

Author(s) -

János Minárovits,

Hans Helmut Niller

Publication year - 2013

Publication title -

medical epigenetics

Language(s) - English

Resource type - Journals

ISSN - 1664-5561

DOI - 10.1159/000354284

Subject(s) - epigenetics , reprogramming , epigenesis , biology , carcinogenesis , neuroscience , dna methylation , bioinformatics , genetics , cancer , cell , gene , gene expression

Patho-epigenetics is a new discipline dealing with the description of pathologic changes elicited by epigenetic dysregulation. Patho-epigenetic processes contribute to the development of both rare syndromes and diseases of high prevalence in human populations. In this short review, we summarize the basic epigenetic regulatory mechanisms in a nutshell and briefly outline how epigenetic reprogramming contributes to all forms of tumorigenesis and plays a role both in the initiation and progression of neoplasms.

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