Open AccessVitamin K Intake, Body Mass Index and Warfarin Maintenance Dose
Author(s) -
Edmond K. Kabagambe,
T. Mark Beasley,
Nita A. Limdi
Publication year - 2013
Publication title -
cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.547
H-Index - 63
eISSN - 1421-9751
pISSN - 0008-6312
DOI - 10.1159/000354218
Subject(s) - body mass index , vitamin , medicine , warfarin , endocrinology , vitamin k epoxide reductase , vkorc1 , cyp2c9 , metabolism , cytochrome p450 , atrial fibrillation
Warfarin inhibits vitamin K-dependent coagulation factors. Being fat-soluble, the availability of vitamin K may vary according to body fat. We hypothesized that body mass index (BMI), a proxy of body fat, may interact with vitamin K intake in determining a warfarin maintenance (WM) dose.
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