G-CSF in Healthy Allogeneic Stem Cell Donors | Zendy

Kristina Hölig | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

G-CSF in Healthy Allogeneic Stem Cell Donors

Author(s) -

Kristina Hölig

Publication year - 2013

Publication title -

transfusion medicine and hemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 39

eISSN - 1660-3818

pISSN - 1660-3796

DOI - 10.1159/000354196

Subject(s) - medicine , granulocyte colony stimulating factor , stem cell , peripheral blood , peripheral blood stem cells , intensive care medicine , mobilization , granulocyte , immunology , surgery , transplantation , hematopoietic stem cell transplantation , chemotherapy , history , genetics , archaeology , biology

Mobilization of peripheral blood stem cells (PBSC) in healthy volunteers with granulocyte colony-stimulating factor (G-CSF) is currently carried out at many institutions worldwide. This report presents the experience of the Dresden center regarding donor evaluation and mobilization schedule. Data regarding efficacy, short- and long-term safety of G-CSF treatment gained from 8290 PBSC collections in healthy donors are outlined. These results are discussed against the background of the available evidence from the literature. Although established as a standard procedure, G-CSF application to allogeneic donors will always be a very delicate procedure and requires the utmost commitment of all staff involved to ensure maximum donor safety.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research