Epidemiological Characteristics of Norovirus Associated with Sporadic Gastroenteritis among Children from the 2006/2007 to 2011/2012 Season in Nara Prefecture, Japan | Zendy

Masaki Yoneda | Zendy; Akiko Okayama | Zendy; Yoshiteru Kitahori | Zendy

Open Access

Epidemiological Characteristics of Norovirus Associated with Sporadic Gastroenteritis among Children from the 2006/2007 to 2011/2012 Season in Nara Prefecture, Japan

Author(s) -

Masaki Yoneda,

Akiko Okayama,

Yoshiteru Kitahori

Publication year - 2013

Publication title -

intervirology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.641

H-Index - 61

eISSN - 1423-0100

pISSN - 0300-5526

DOI - 10.1159/000353852

Subject(s) - norovirus , epidemiology , genotype , feces , acute gastroenteritis , molecular epidemiology , virology , caliciviridae , medicine , biology , outbreak , microbiology and biotechnology , gene , genetics

The present study aimed to describe the epidemiological characteristics of norovirus (NoV) associated with sporadic gastroenteritis in regional populations of Nara Prefecture, Japan, from the 2006/2007 to 2011/2012 epidemic season. Fecal specimens of sporadic gastroenteritis collected between September 2006 and August 2012 in Nara Prefecture were examined for the presence of NoV by reverse transcription-polymerase chain reaction. The NoV genotype was determined by nucleotide sequence analysis. In total, 274 NoVs associated with sporadic gastroenteritis were identified. We detected 10 different NoV genotypes: GI/3, GI/4, GI/8, GII/2, GII/3, GII/4, GII/6, GII/7, GII/12, and GII/13. A high NoV detection rate of 35.9% was identified in 1-year-old children. Among the 274 NoV isolates, 142 were obtained from males and 131 were obtained from females (the source of one was unknown). The most prevalent genotype was GII/4, accounting for 117 of the 192 different NoVs identified by sequencing. More epidemiological data will be required to determine the epidemiological characteristics of NoVs in other areas of Japan.

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