Hepatitis B Virus Genotype D Predominates HBsAg-Positive Egyptian Blood Donors and Is Mainly Associated with a Negative HBeAg Serostatus
Author(s) -
Febee E. Habil,
Wafaa K.M. Mahdi,
Sayed F. Abdelwahab,
Mohamed Abdel-Hamid
Publication year - 2013
Publication title -
intervirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.641
H-Index - 61
eISSN - 1423-0100
pISSN - 0300-5526
DOI - 10.1159/000353105
Subject(s) - hbsag , genotype , hepatitis b virus , genotyping , hbeag , virology , medicine , serostatus , seroprevalence , hepatitis b , cccdna , virus , immunology , antibody , biology , serology , viral load , gene , genetics
Hepatitis B virus (HBV) infection is a global health burden. In this regard, Egypt has an intermediate HBV seroprevalence. HBV is classified into ten different genotypes (A-J) with different geographic distributions. Genotype D is the most prevalent in the Middle East. Limited data are available about HBV genotyping among Egyptian blood donors, particularly in Upper Egypt. We examined the seroprevalence of HBV among 12,000 blood donors attending the blood transfusion services center in Minia Governorate, Upper Egypt.
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