Estimating the Range of Obesity Treatment Response Variability in Humans: Methods and Illustrations | Zendy

Kathryn A. Kaiser | Zendy; Gary L. Gadbury | Zendy

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Estimating the Range of Obesity Treatment Response Variability in Humans: Methods and Illustrations

Author(s) -

Kathryn A. Kaiser,

Gary L. Gadbury

Publication year - 2013

Publication title -

human heredity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.423

H-Index - 62

eISSN - 1423-0062

pISSN - 0001-5652

DOI - 10.1159/000351738

Subject(s) - obesity , demography , waist , population , medicine , statistics , biology , mathematics , sociology

The rising prevalence of human obesity worldwide has focused research on a variety of interventions that result in highly varied degrees of weight loss (WL). The advent of genomic testing has quantified estimates of both the contribution of genetic factors to the development of obesity as well as racial/ethnic variation of risk alleles across subpopulations. More recent studies have examined genetic associations with effectiveness of WL interventions, but to date are unable to explain a large proportion of the variance observed.

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