A Common APOE Polymorphism Is an Independent Risk Factor for Reduced Glomerular Filtration Rate in the Spanish RENASTUR Cohort | Zendy

Eliécer Coto | Zendy; Juan Manuel López Gómez | Zendy; Beatriz Tavira | Zendy; Salvador Tranche | Zendy; Francisco B. Ortega | Zendy; María I. Rodríguez | Zendy; Emilio Sánchez | Zendy; Rafael Marín | Zendy; Ana I. Corao | Zendy; J.C. Arenas | Zendy; Victoria Álvarez | Zendy

Open Access

A Common <b><i>APOE</i></b> Polymorphism Is an Independent Risk Factor for Reduced Glomerular Filtration Rate in the Spanish RENASTUR Cohort

Author(s) -

Eliécer Coto,

Juan Manuel López Gómez,

Beatriz Tavira,

Salvador Tranche,

Francisco B. Ortega,

María I. Rodríguez,

Emilio Sánchez,

Rafael Marín,

Ana I. Corao,

J.C. Arenas,

Victoria Álvarez

Publication year - 2013

Publication title -

cardiorenal medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.661

H-Index - 21

eISSN - 1664-3828

pISSN - 1664-5502

DOI - 10.1159/000351158

Subject(s) - medicine , cohort , renal function , polymorphism (computer science) , risk factor , gastroenterology , endocrinology , genetics , gene , biology , allele

APOE gene variants may contribute to the risk of chronic kidney disease. Our aim was to determine whether the common APOE -ε2/ε3/ε4 polymorphism is associated with a reduced estimated glomerular filtration rate (eGFR) in the RENASTUR population, a cohort of elderly individuals from the region Asturias (northern Spain).

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